Doi: 10.5578/tt.8279
Tuberk Toraks 2014;62(4):324
QuantiFERON-TB gold in-tube test ile t?berk?lin cilt testinin kar??la?t?rmas?
Sim Sai TIN1, Viroj WIWANITKIT2
1 Shantou T?p Merkezi, Shantou, ?in
1 Shantou Medical Center, Shantou, China
2 Hainan ?niversitesi T?p Fak?ltesi, Tropikal Hastal?klar, Hakou, ?in
2 Department of Tropical Medicine, Faculty of Medicine, Hainan University, Hakou, China
We would like to discuss on the publication on "QuantiFERON-TB gold in-tube test with tuberculin skin test (1)." Metin Timur et al. concluded that "as a result of the study it is suggested to confirm positive TST results with tests based on interferon-gamma (IFN-γ) because it can reduce false positive diagnosis and treatment of latent tuberculosis infection (1). "In fact, QuantiFERON-TB gold in-tube test is the new test that is widely mentioned for its usefulness (2,3).? However, it should be noted that the QuantiFERON-TB gold in-tube test is not exactly superior to standard tuberculin skin test. According to a report by? Verhagen et al., it was noted that "replacement of TST by the QFT-GIT for detection of Mycobacterium tuberculosis infection is not recommended in this resource-constrained setting as test results showed substantial concordance and TST positivity was not affected by previous BCG vaccination (4)." Rutherford et al. also noted that "QFT-GIT offers little advantage over the TST (5)".
CONFLICT of INTEREST
None declared.
REFERENCES
Yaz??ma Adresi (Address for Correspondence)
Dr. Sim Sai TIN
Shantou T?p Merkezi,
SHANTOU - CHINA
e-mail: simsaitin@gmail.com