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doi:10.5578/tt.8936
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β-HCG secretion by a non-small cell lung cancer: a case report

Burcu CİRİT KOÇER1, Yurdanur ERDOĞAN1, Berna AKINCI ÖZYÜREK1, Sertaç BÜYÜKYAYLACI ÖZDEN1,
Funda DEMİRAĞ2


1 Clinic of Chest Diseases, Ankara Ataturk Chest Diseases and Chest Surgery Training and Research Hospital,

Ankara, Turkey

2 Clinic of Pathology, Ankara Ataturk Chest Diseases and Chest Surgery Training and Research Hospital, Ankara, Turkey

SUMMARY

β-HCG secretion by a non-small cell lung cancer: a case report

Paraneoplastic secretion of beta human chorionic gonadotropin (β-HCG) in non-small cell lung cancer (NSCLC) has been rarely reported. A 43-year old male patient was admitted with dyspnea and chest pain. Thorax computed tomography (CT) revealed bilateral multiple masses and pleural effusion at right hemithorax. Positron emission tomography (PET)-CT showed pathologic 18 FDG uptake at mass lesions and mediastinal lymph nodes. The serum β-HCG level was elevated. A bronchoscopy was performed and endobronchial lesion was observed. Since a definitive diagnosis was not achieved by pathologic examination of biopsy specimen, bronchoscopy was repeated and a sample was taken by cryobiopsy. The pathologic examination revealed non-small cell lung cancer.In conclusion, the case was presented because of extremely rare occurence of NSCLC secreting β-HCG.

Key words: β-HCG, non-small cell lung cancer, gynaecomastia

Received: 13.01.2015 • Accepted: 04.02.2015

Address for Correspondence

Dr. Burcu CİRİT KOÇER

Ankara Atatürk Göğüs Hastalıkları ve

Göğüs Cerrahisi Eğitim ve Araştırma Hastanesi,

Göğüs Hastalıkları Kliniği,

ANKARA - TURKEY

e-mail: drcirit@hotmail.com

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