Validity and reliability of "asthma quality of life questionnaire" in a sample
of Turkish adult asthmatic patients
ÖZGEN ALPAYDIN1, Arzu YORGANCIOĞLU1, Özge YILMAZ2,
Mine BORA1, Tuğba GÖKTALAY1,
of Chest Diseases, Faculty of Medicine, Celal Bayar University, Manisa, Turkey,
of Pediatric Allergy and Respiration Unit, Department of Children's Health and
Celal Bayar University, Manisa, Turkey.
to investigate the validity and reliability and of "Asthma Quality of Life
Questionnaire (AQLQ)" in Turkish adult asthmatic patients. New or previously
diagnosed [according to Global Initative for Asthma (GINA) 2008] symptomatic
118 consecutive stable asthmatic patients between 18 and 55 years old were
included. Asthma severity was determined and Turkish adaptation of the AQLQ was
administered. Lara asthma symptom scales (LASS), pulmonary function tests,
Turkish adaptation of Medical Outcomes Survey Short Form-36 (SF-36) were
evaluated. All assessments were done twice at recruitment and after 10 weeks.
During this period patients were allowed to make modifications on their
medication when necessary. Among the recruited 118 patients 95 were female and 14
were lost in the follow-up. Sixty-two percentages of the patients had mild and
38% moderate asthma. The internal consistency of AQLQ was high (Cronbach's
alpha 0.81-0.87) and item-total score correlations were ranging from 0.75-0.89.
The cross-sectional and longitudinal correlations between AQLQ total and domain
scores and SF36 domain scores were in a range of little or fair degree (r=
0.241-0.626, p< 0.005). Total AQLQ scores were observed significantly
different according to disease severity and LASS both in the first (p<
0.001, both) and 10 weeks follow-up visits (p= 0.006, p< 0.001
respectively). A statistical significant change was observed in AQLQ symptom
score as in total LASS changed (p< 0.001, both) in the follow-up. Our
results demonstrated that Turkish version of AQLQ is feasible, reliable, valid
and sensitive to changes in adult asthmatics.
Words: Asthma, quality of life, validity, reliability.
Address for Correspondence:
Aylin Özgen AlpaydIn,
Eylül Üniversitesi Tıp Fakültesi,
Hastalıkları Anabilim Dalı,